Yes, you can use multiple XFX graphics cards in SLI or CrossFire configurations, depending on the specific models of the cards you are using. SLI, which is NVIDIA's technology, can be utilized with compatible XFX GeForce graphics cards. CrossFire is the equivalent technology from AMD and can be used with compatible XFX Radeon graphics cards. In both cases, it is essential to ensure that the motherboards being used support either SLI or CrossFire and are configured correctly to harness the power of multiple graphics cards.
When setting up multiple graphics cards, it is also important to check that your power supply can handle the additional power requirements and that proper cooling is in place to manage the increased heat generated. Furthermore, both SLI and CrossFire can deliver significant performance improvements in certain gaming scenarios, but not all games benefit equally from these technologies.
For additional details, including compatibility and setup instructions, it may be useful to explore the product pages on the XFX website or other associated resources, which could provide useful information about supported configurations.