Yes, a Netgear router can be used with a modem from a different brand. Compatibility between routers and modems is generally not brand-specific, as long as the modem is compatible with the Internet service provider and adheres to standard protocols like DOCSIS for cable modems. To set up a Netgear router with a third-party modem, it is important to connect the router to the modem using an Ethernet cable, ensuring that it is plugged into the WAN or Internet port on the router. After this connection is made, users can configure the router through a web interface to complete the setup process. If there are any specific settings required by the Internet service provider, such as PPPoE credentials or any subnet configurations, these should be inputted in the router settings. For detailed information on the setup process, one might consider visiting the current web page dedicated to Netgear support and setup resources.