The number of tissues in a Kleenex box can vary depending on the specific product line and box size. Typically, a standard rectangular box of Kleenex facial tissues contains between 60 to 200 tissues. For example, the classic rectangular boxes often hold around 120 tissues, while smaller boxes may hold closer to 60 tissues. Additionally, there are larger boxes designed for home or office use that may contain 200 or more tissues. It is always a good idea for consumers to check the packaging for exact details regarding tissue count, as this information is usually listed clearly on the box. For more specific information, visiting kleenex.com may provide additional insights and options.